I-Curcumin

I-Turmeric isetshenziswe abantu cishe iminyaka eyizinkulungwane ezine. Sekuyizinkulungwane zeminyaka isetshenziswa njengodayi, njengesinongo sokupheka, nanjengento esetshenziswa kwezokwelapha. Imibhalo yesiSanskrit yokusetshenziswa kwayo njengezinongo isuka ezikhathini zasendulo zamaNdiya. Igama elithi Turmeric livela kwelesiLatini elithi Terra merita ngoba izimpande zalo, uma ziphansi, ziyigolide. Isinongo senziwe ngesitshalo se-turmeric (Curcuma longa) emndenini wejinja. I-Turmeric itshalwa ngeziqu zayo. Isiqu siyayomiswa bese sigaywa sibe yimpushana ephuzi enokunambitheka okubabayo esikwaziyo nesikuthandayo.

Isithako esiyinhloko se-turmeric esidonse ukunaka i-Curcumin. Kube nemibiko yokuthi ama-polyphenols afana ne-curcumin anezakhiwo zemithi, okuhlanganisa ukusiza ukulawula izimpendulo ezivuthayo, izifo zamehlo eziwohlokayo, kanye nesifo se-metabolic. Ama-Polyphenols ama-metabolite ezitshalo asiza ukuvikela izitshalo emisebeni ye-ultraviolet, izinambuzane, amagciwane kanye namagciwane. Futhi ziwumthombo wokubaba, i-asidi, umbala, ukunambitheka, namandla e-oxidizing.

Ayini ama-polyphenols

Ama-polyphenols, afana ne-curcumin, athole ukuthandwa ngoba izifundo ze-epidemiological ziye zabonisa ngokuphindaphindiwe ukuthi ukudla okucebile kuzo kunganikeza ukukhululeka kokuvuvukala. Ezingeni lamangqamuzana, ama-polyphenols asiza ukuzinzisa i-oxidation ezingxenyeni zamaselula. I-oxidation ingaholela ekulimaleni kwama-organelles ngaphakathi kwamaseli, kufaka phakathi i-mitochondria, "izindlu zamandla zamaseli" lapho amandla amaningi eseli akhiqizwa umoya-mpilo esiwuphefumulayo. Ukudla ukudla okunezakhiwo ze-antioxidant, njengamajikijolo, amantongomane, amafutha anempilo, kanye ne-turmeric, kucatshangwa ukuthi kusiza ukugcina amazinga omonakalo we-oxidative.

Iyiphi inzuzo i-curcumin enayo

Ucwaningo oluningi olubuyekeziwe luye lwaphakamisa ukuthi i-curcumin ingasiza ekunciphiseni izimpawu zokucindezeleka kwe-oxidative egazini ngokuthinta umsebenzi wama-enzyme anciphisa ama-radicals mahhala. Impendulo yokuvuvukala kuwuchungechunge oluyinkimbinkimbi lokusabela kunoma yisiphi izicubu ezisekelwe ekushukumiseni kwangaphakathi noma kwangaphandle. Umgomo uwukuvikela izicubu nokususa imbangela yokuqala yokulimala kwamangqamuzana. Kodwa-ke, impendulo yokuvuvukala engalawulwa isikhathi eside ingaholela ekulimaleni kwezicubu ngaphezu kokulindela.

Ukuze ukhiqize lolu chungechunge lokusabela kwamakhemikhali, ama-molecule okubonisa akhiqizwa futhi akhululwe yiseli, okuholela ekuphenduleni kokuvuvukala okungaphezulu kanye nomjikelezo oqhubekayo wamangqamuzana nama-molecule, okusho ukuthi impendulo yokuvuvukala iba nzima kakhulu. Ucwaningo oluningi luye lwabonisa ukuthi i-curcumin ivimbela lezi zibonakaliso zeselula, ngaleyo ndlela isiza ukugcina inani lamaprotheni okuphendula ukuvuvukala namaseli. Kodwa-ke, kweziningi zalezi zifundo, abacwaningi bathole ukuthi i-curcumin ine-bioavailability empofu.

Ngakho-ke, ngemva kokuba i-curcumin idliwe emzimbeni, kunzima ukuthi i-gastrointestinal tract imunce, i-metabolize futhi isuse ngokushesha emzimbeni. Ukusebenzisa i-curcumin ekudleni okucebile nge-lecithin, njengamaqanda, uwoyela wemifino, nebhotela, kungasiza ekwandiseni ukumuncwa kwayo emathunjini. Ucwaningo oluhlanganisa i-curcumin ne-piperine, isithako semvelo sikapelepele omnyama, lubonise ukuthi ngenxa yokuthi i-piperine ibambezela ukugaywa kwe-curcumin, inyusa amazinga e-curcumin ngesici esingama-20.

Iyini imiphumela yempendulo yokuvuvukala

Kubalulekile ukukhumbula ukuthi impendulo yokuvuvukala iyimpendulo yemvelo yomzimba ekushukumiseni. Kunezigaba ezimbili ezibanzi zezimpendulo zokuvuvukala. Ukusabela okunamandla okuvuvukalayo kuhlala isikhathi esifushane futhi kuvame ukuvuswa isisusa sesikhashana esifana nebhaktheriya, igciwane, noma ukulimala.

Kodwa-ke, uma impendulo yokuvuvukala iqhubeka, impendulo yokuvuvukala izodlulela esigabeni sesibili. Lesi sigaba sibizwa ngokuthi yisigaba esingamahlalakhona, futhi uma siyekwa singalawulwa, singaholela ezinhlobonhlobo zezifo ezingelapheki. Ezinye izimpawu zokusabela kokuvuvukala okungapheli aziqondile futhi zingase zihlanganise ubuhlungu bamalunga, ubuhlungu bomzimba, ukukhathala okungapheli, ukuqwasha, ukucindezeleka, nokuzuza isisindo noma ukuncipha.

Izinkinga zamalunga - ikakhulukazi izinkinga zamathambo namalunga - kucatshangwa ukuthi zihlotshaniswa nokusabela okungapheli kokuvuvukala. Ezinye izifundo ziphakamisa ukuthi isithasiselo sansuku zonke se-500 milligrams kuya ku-2 amagremu we-curcumin singathuthukisa ubuhlungu bamadolo.

Nakuba ucwaningo aluzange lubonise ukwehla kwabamaka bempendulo yokuvuvukala egazini, imiphumela icatshangwa ukuthi ibangelwa amaprotheni avuthayo akhona endaweni ehlangene. Olunye lwezifundo lubonise ubuhlungu obuhlangene budambisiwe emahoreni amabili ngesithasiselo se-curcurin kanye nehora elilodwa ngesidakamizwa esiphendula ukuvuvukala okungezona i-steroidal, i-ibuprofen, isidakamizwa esinconyelwe izinkinga ezihlangene. Isikhathi se-curcumin supplementation sasiyi-4 kumaviki angu-12.

I-Metabolic syndrome, ehlobene eduze nesifo se-glycometabolic type II, ingesinye isifo esingase sihlotshaniswe nezimpendulo zokuvuvukala. Iqukethe izinhlobonhlobo zezimpawu, okuhlanganisa ukumelana ne-insulin, amazinga aphakeme kashukela egazini, umfutho wegazi ophakeme, i-triglycerides ephakeme, i-HDL ephansi, i-cholesterol "enhle", i-LDL ephezulu, i-cholesterol "embi" kanye nokukhuluphala. Ucwaningo oluningi nge-curcumin kanye nesifo se-metabolic lubonise ukuthi i-curcumin ingakwazi ukwandisa ukuzwela kwe-insulin, ilawule umfutho wegazi, kanye nezimpawu zokuvuvukala.

Ucwaningo olulodwa lwabonisa ukuthi ukugcwalisa nge-1 gram ye-curcumin inyanga kunciphisa amazinga e-triglyceride, kodwa kwakungekho shintsho ku-cholesterol noma amazinga amafutha emzimbeni. Ucwaningo luye lwabonisa nokuthi izimpendulo zokuvuvukala, i-triglycerides ephezulu kanye ne-cholesterol ephezulu konke kwandisa ingozi yesifo senhliziyo. Ukwengezwa kwe-Curcumin kukholakala ukuthi kusiza ukunciphisa ingozi ehambisanayo.

Ungayithatha kanjani i-curcumin

I-Curcumin kuma-curries isilinganiso esingaba ngu-3% wesisindo esomile. Amatiye nezinye iziphuzo ze-con/aining turmeric, ezifana nobisi lwegolide, ezinye izindlela eziphuzwayo ezizuza ezicini ezilwa nokuvuvukala ze-curcumin. Njengokhari, okuqukethwe kwe-curcumin nakho kuyahlukahluka.

Izithako zokudla ze-Curcumin eziqukethe izimpande ze-curcumin zingenye indlela yokuthatha i-curcumin. Amalebula ezengezo azokhombisa amaphesenti ahlukene okukhishwa kwe-curcumin. Ukulawulwa kwekhwalithi okuzimele kanye namalabhorethri okuqinisekisa ikhwalithi ahlola futhi ahlole umkhiqizo ukuze kuqinisekiswe lezi zimangalo futhi kugunyazwe ilebula njengoba iqondiswa umkhiqizi womkhiqizo. Amanye ama-curcumin supplementary supplements angahle aqukathe ezinye izingcaphuno, ezifana ne-black pepper extract (piperine) noma izingxube zobunikazi eziqukethe izinsini zemifino, noma amanye amalungiselelo e-lipid, ngomzamo wokuthuthukisa i-bioavailability ye-curcumin. Ikakhulukazi, ucwaningo luye lwabonisa ukuthi i-curcumin ingasetshenziswa njenge-agent ye-topical ekwakhiweni kwamafilimu e-collagen, ama-lotions, ama-sponges nama-bandages ukukhuthaza isikhumba esinempilo.

Umthamo kanye nokuqinisekiswa kwezithako ze-curcumin

I-Curcumin ivunyelwe yi-US Food and Drug Administration njengenhlanganisela epholile. Imithamo enconyiwe eyeqisayo yansuku zonke isuka ku-3 mg/kg iye ku-4-10 g/day. Njengoba izifundo eziningi ezisebenzisa i-extract zinesikhathi somkhawulo wezinyanga ezingu-1-3, kuze kube manje, abukho ubufakazi banoma yimiphi imiphumela yesikhathi eside kusukela ekusetshenzisweni kwesikhathi eside kwe-curcumin. Nakuba kungakaze kube nemibiko yokusabela okubi kakhulu ekusetshenzisweni kwe-curcumin, eminye imiphumela emibi ingase ihlanganise isifo sohudo, ubuhlungu bekhanda, ukuqubuka kwesikhumba, nezihlalo eziphuzi.

Uma uthatha imithi, thintana nodokotela wakho ngaphambi kokucabangela ukuqala izithako ze-curcumin. Ucwaningo lwe-in vitro lubonise ukuthi i-curcumin inyusa ingozi yokopha ezigulini ezithatha ama-diluent ngasikhathi sinye, ngakho-ke noma yikuphi ukusebenzisana kwezidakamizwa okungenzeka noma okukukhathazayo kufanele kuxoxwe nodokotela wakho. Kubuye kube nemibiko ye-curcumin powder ebangela ukungezwani komzimba ekuthinteni, njengokuluma noma ukuqubuka ngokushesha ngemva kokuxhumana.

Uma kwenzeka noma iyiphi yalezi zimpawu, yeka ukusebenzisa ngokushesha. Kubaluleke kakhulu ukuyeka ukusebenzisa noma yimiphi imikhiqizo equkethe i-curcumin futhi ushayele izinsizakalo eziphuthumayo zendawo yakho uma uzwa noma yikuphi ukushaywa umoya, ukuphefumula kanzima, ubunzima bokugwinya noma ukuvuvukala kwezindebe.

Sekukonke, i-curcumin ibonisa amandla amakhulu njengenye into futhi ingasiza ekugcineni imisebenzi enempilo. Kuyisinongo esihle ukwengeza ukunambitheka okuqabulayo nombala ekudleni, ikakhulukazi inkukhu nemifino. Hlanganisa amajikijolo, inyama engenamafutha, namafutha anempilo, futhi ukudla kwakho kuzogcwala ama-polyphenols.

Khumbula, uma ukhetha ukuqala ukuthatha noma yisiphi isithasiselo sokudla, qiniseka ukuthi ubonana nodokotela wakho futhi uqiniseke ukuthi ufunda ilebula yomkhiqizo ngokucacile kuqala ukuze unqume inani le-curcumin okufanele lidliwe.